Suicidal Ideation Common in Women Seeking Treatment for Premenstrual Dysphoric Disorder

In our clinic, we see many women of all ages who current with suicidal ideation emerging or worsening in the course of the premenstrual section of the menstrual cycle.  Despite the fact that past research have reported an affiliation concerning Premenstrual Dysphoric Disorder (PMDD) and suicidal ideation, most of these scientific tests have not confirmed the prognosis utilizing future scores and DSM diagnostic standards.  A the latest research from Wikman and colleagues assesses the prevalence of suicidal ideation in women with PMDD confirmed employing additional stringent criteria..

In this research, the members were 110 females recruited to participate in a randomized placebo-managed clinical demo for the cure of PMDD amongst January 15, 2017 and Oct 19, 2019. The diagnosis of PMDD was verified making use of potential each day rankings in line with DSM-5 criteria. Latest suicidal ideation was measured utilizing the MADRS-S administered for the duration of the late luteal phase of the menstrual cycle.  

Suicidal ideation was described for the duration of the late luteal stage by just about 40% of the ladies with confirmed PMDD (n = 43, 39.1%).  Current suicidal ideation was a lot more frequent in gals reporting past psychological cure for PMDD (OR 5.63, 95% CI 1.07-29.49).  In addition, larger depressive symptoms during the late luteal stage had been affiliated with suicidal ideation  (OR 1.17, 95% CI 1.10-1.25).  In distinction, higher rankings of self-rated overall health were being related with decreased odds ratios for present-day suicidal ideation (OR .98, 95% CI .96-.99).

In this inhabitants trying to find procedure for PMDD, suicidal ideation is pretty popular, impacting about 40% of the females.  This examine is unique from prior studies analyzing the association concerning PMDD and suicidal ideation in the present-day examine, the analysis of PMDD was verified prospectively in accordance to DSM diagnostic standards and suicidal ideation was calculated concurrently.  While the study does not assess suicidal ideation in a neighborhood sample of girls with PMDD, the findings of this study suggest that suicidal ideation is typical amongst women searching for procedure for PMDD.  

Ruta Nonacs, MD PhD

Wikman A, Sacher J, Bixo M, Hirschberg AL, Kopp Kallner H, Epperson CN, Comasco E, Sundström Poromaa I. Prevalence and correlates of existing suicidal ideation in females with premenstrual dysphoric ailment. BMC Womens Health. 2022 Feb 1122(1):35.

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